航班蛇患

黑帮老大艾迪•金策划了一起凶杀案，被偶然路过的年轻人西恩•琼斯（Nathan Phillips 饰）目击。为了在法庭上成功指控这个作恶多端的黑社会头子，警方派出资深联邦密探尼维利•费恩（Samuel L. Jackson 饰）负责保护西恩，并将其从夏威夷护送至洛杉矶法庭。为避免证人遇害，尼维利采取声东击西的策略，与西恩偷偷乘上一架普通的红眼航班。 　　然而这项绝密的计划被艾迪安排在警方的内奸获知，为了逃脱法律制裁，艾迪派出携带大量毒蛇的杀手登上飞机，一场离奇恐怖的血腥灭口案件就此展开……While practicing motocross in Hawaii, Sean Jones witnesses the brutal murder of an important American prosecutor by the powerful mobster Eddie Kim. He is protected and persuaded by the FBI agent Neville Flynn to testify against Eddie in Los Angeles. They embark in the red-eye Flight 121 of Pacific Air, occupying the entire first-class. However, Eddie dispatches hundred of different species of snakes airborne with a time operated device in the luggage to release the snakes in the flight with the intent of crashing the plane. Neville and the passengers have to struggle with the snakes to survive.