冰（杨千嬅 饰）是广告公司的客户经理，公司她是女强人，下班后她跟很多女人一样，苦苦寻觅自己的爱情。一天晚上她在酒吧遇到了心理医生V仔（任贤齐 饰），两个人缠绵的时候V仔意外发现了冰的胸部有肿块。经医生诊断证实冰真的患上了乳癌，冰大受打击，惧怕自己因为失去了一边乳房而没有好归宿。 自从因为V仔发现自己的病情后，冰就对V仔存在了怨恨，可是V仔也因为她留下了阴影，因此不举。冰差点被朋友骗财，幸好有V仔及时解围，之后二人便互相扶持帮助，情愫暗生。冰同时要为是否切除乳房而烦恼。A regular white-collar woman named Bing, who leads a carefree city life that includes guarding her turf in the office and dating and gossiping with her three girlfriends. However, her carefree life soon turns upside down when she found a lump in her breast. Everything begins to fall apart as she tries to cope with the loss of femininity in a series of bittersweet events. With the help of a happy-go-lucky doctor V and a shy but talented teenager Sing, Bing begins to find new meanings in her turmoil and the will to face her own demons.
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