《濑户内少年棒球团》以战后的兵库县淡路岛为舞台,以备受孩子们憧憬的美女老师中井驹子为主人公。中井老师为了通过棒球带给学生们勇气和梦想,与丈夫一同组建了棒球队“江坂Tigers”。Set after World War II on Awaji Island in Hyogo Prefecture, Komako is a teacher at an elementary school. She and her students decide to form a boys' baseball team with Komako as their coach.